Which of the responses is (are) correct? Creatine kinase (CK)?


1    is found in skeletal muscle

2    isoenzyme fractions are used to identify the type of tissue damaged

3    CK-MB are detected in blood within 3–5 h of a myocardial Infarction.


A    if 1, 2 and 3 are correct

B    if 1 and 2 only are correct

C    if 2 and 3 only are correct

D    if 1 only is correct

E    if 3 only is correct.




  1. A is the answer and the winners are Nikitn and Aliyu.
    Details Below:
    Creatine kinase (CK) is an enzyme that is found in heart muscle, skeletal muscle
    and the brain. There are three isoenzymes: CK-BB (CPK1) which is pre-
    dominantly found in the brain and lungs, CK-MB (CPK2) mainly found in myo-
    cardial cells and CK-MM (CPK3) which consists of circulatory CK. Creatine
    kinase blood levels rise when these muscle or nerve cells are injured.Differential elevations of the three isoenzymes indicate the type of tissue that
    has been damaged. A rise in CK-BB occurs after a cerebrovascular accident
    or pulmonary infarction. CK-MB is elevated after a myocardial infarction and
    in unstable angina. However, severe skeletal muscle injury may also elevate
    CK-MB. CK-MM levels are increased in myopathies, after vigorous exercise or


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