pharmacy
Tamsulosin hydrochloride is anantagonist of alpha 1A adrenoceptors in the prostate.
Its structural formula is:
Each TAMSULON-XL (tamsolosin HCI) sustained release capsule for oral administration contains tamsulosin HCI 0.4 mg
Each hard gelatin capsule contains:
Tamsulosin Hydrochloride BP 400mcg.
(As Sustained Release Granules)
Clinical Pharmacology:
Tamsulosin, an alpha 1 adrenoceptor blocking agent, exhibits selectivity for alpha 1 receptor in the human prostate. At least three discrete alpha 1-adrenoceptor subtypes have been identified: alpha 1A, alpha 1B and alpha 1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha 1– receptors in human prostate of the alpha 1A subtype.
