Things you may not know about Aspirin

5
1036
pharmacy

Aspirin:
1 potentiates the anticoagulant effect of warfarin
2 inhibits platelet aggregation
3 promotes vitamin K synthesis

ONE or MORE of the responses above is (are) correct. Decide which of the responses is
(are) correct. Then choose:
A if 1, 2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct

5 COMMENTS

  1. B is the answer, and Clement is the winner.
    Details:
    Because of its antiplatelet effect, the administration of aspirin to patients receiv￾ing warfarin is associated with a potentiated anticoagulant effect leading to
    an increased risk of bleeding. Aspirin decreases platelet aggregation by
    inactivating cyclo-oxygenase, an enzyme involved in the platelet aggregationpathway through the interference with thromboxane A2. Vitamin K is required
    for the procoagulation activity. Aspirin does not interfere with vitamin K synthe￾sis. However warfarin, which is an oral anticoagulant, acts as a vitamin K
    antagonist.

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