Which of the Following Statements Concerning Vitamin B12?


Which of the following statements concerning vitamin B12 (cyanocobalamin) functions are true:

a) Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems

b) Essential constituent of coenzyme A, the important coenzyme for acyl transfer in the TCA cycle and de novo fatty acid synthesis

c) Coenzyme for numerous metabolic reaction, including transformation of methylamlonyl CoA to succinyl CoA in the metabolism of propionate; DNA synthesis (acts in concert with folic acid); transmethylation e.g. methionine synthesis from homocysteine

d) An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable



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