A drug with a high first-pass metabolism will have:
A. Increased bioavailability
B. Reduced oral bioavailability
C. Prolonged half-life
D. Increased renal clearance
The volume of distribution (Vd) is best described as:
A. Amount of drug excreted
B. Drug concentration in plasma
C. Theoretical volume that relates drug amount to plasma concentration
D. Rate of drug metabolism
1.b
2.b
B
C
B
C
B
C
1. B
2. C
1.B
2. C
B
C
B
C
1 B
2 C