Home PANS Quiz of the Day A patient is taking a drug that is highly protein bound.

A patient is taking a drug that is highly protein bound.

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A patient is taking a drug that is highly protein bound. Another medicine is introduced that has a greater affinity for the same plasma protein-binding site. Assuming the displaced drug has a small volume of distribution, what is the most immediate pharmacokinetic consequence?

A. Decreased free-drug concentration and reduced effect
B. Increased free-drug concentration and potentially increased effect
C. Increased hepatic first-pass metabolism and reduced effect
D. Decreased renal filtration and prolonged absorption

A pharmacy student is asked to identify a compound that contains a benzene ring infused to a five-membered heterocyclic ring containing two nitrogen atoms, with the heteroatoms occupying positions 1 and 3 of the five-membered ring. Which heterocyclic nucleus is being described?

See also  Which of the following is the best example of a narrow therapeutic index medicine?

A. Indole
B. Benzimidazole
C. Benzoxazole
D. Quinazoline

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