A patient on digoxin develops severe nausea, confusion, and yellow vision after starting clarithromycin. The interaction is due to:
A. CYP3A4 inhibition
B. P-glycoprotein inhibition
C. CYP2C9 inhibition
D. Increased renal clearance
A patient on lithium for bipolar disorder is started on hydrochlorothiazide. Which is the main pharmacokinetic effect?
A. Lithium clearance increases
B. Lithium clearance decreases
C. Lithium bioavailability decreases
D. Lithium protein binding decreases
B,B
B,B
V
B
B,B
B,B
1)B
2)B
1.B
2.B