Peptic Ulcer (Quiz of the Day)


Which of the following products is NOT indicated for the management
of peptic ulceration?
A Zantac
B Gaviscon
C Nexium
D Pariet
E Buscopan


  1. The answer is E, and details below explain.

    Buscopan contains hyoscine, which is a quaternary ammonium compound having antimuscarinic activity. It is indicated for symptomatic relief of gastrointestinal or genitourinary disorders characterised by smooth muscle spasm. Zantac contains ranitidine, which is an H2-receptor antagonist that promotes healing of peptic ulcers by reducing gastric output as a result of histamine H2- receptor blockade. Nexium contains esomeprazole and Pariet contains rabeprazole, both of which are proton pump inhibitors. The proton pump inhibitors inhibit gastric acid output by blocking the hydrogen–potassium– adenosine triphosphatase enzyme system of the gastric parietal cells. Gaviscon is an antacid preparation that can be used for the management of symptoms of peptic ulceration. The constitution of Gaviscon preparations varies according to dosage forms. Gaviscon tablets contain alginic acid, dried aluminium hydroxide, magnesium trisilicate and sodium bicarbonate, whereas Gaviscon liquid contains sodium alginate, sodium bicarbonate and calcium carbonate.

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