pharmacy
1 is found in skeletal muscle
2 isoenzyme fractions are used to identify the type of tissue damaged
3 CK-MB are detected in blood within 3–5 h of a myocardial Infarction.
A if 1, 2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct.
A is the answer and the winners are Nikitn and Aliyu.
Details Below:
Creatine kinase (CK) is an enzyme that is found in heart muscle, skeletal muscle
and the brain. There are three isoenzymes: CK-BB (CPK1) which is pre-
dominantly found in the brain and lungs, CK-MB (CPK2) mainly found in myo-
cardial cells and CK-MM (CPK3) which consists of circulatory CK. Creatine
kinase blood levels rise when these muscle or nerve cells are injured.Differential elevations of the three isoenzymes indicate the type of tissue that
has been damaged. A rise in CK-BB occurs after a cerebrovascular accident
or pulmonary infarction. CK-MB is elevated after a myocardial infarction and
in unstable angina. However, severe skeletal muscle injury may also elevate
CK-MB. CK-MM levels are increased in myopathies, after vigorous exercise or
surgery.
C
D
B
Comment:A
A