pharmacy
A drug that is an antagonist is:
A ❏ valsartan
B ❏ lisinopril
C ❏ morphine
D ❏ simvastatin
E ❏ insulin
Test Your Knowledge On Drug Antagonism
A drug that is an antagonist is:
A ❏ valsartan
B ❏ lisinopril
C ❏ morphine
D ❏ simvastatin
E ❏ insulin
A is the answer, Collins and O’can are winners.
Valsartan is an angiotensin-II receptor antagonist that blocks the actions of
angiotensin resulting in lowering of blood pressure. Lisinopril is an angiotensinconverting enzyme (ACE) inhibitor that inhibits the conversion of angiotensin
I to angiotensin II. Angiotensin I is an inactive precursor of angiotensin II that
has a variety of activities including vasoconstriction. Morphine is an opioid
analgesic that acts as an agonist at endorphin receptors. Simvastatin is a statin
that acts by competitively inhibiting the enzyme HMG-CoA (3-hydroxy-
3-methyl-glutaryl-CoA) reductase that controls the synthesis of cholesterol in the
liver. Insulin is a peptide that is normally produced by the pancreas.
D
A
B
A
B
B
A
A
A