What do you know about Mesalazine?

9
470

A     should be avoided in patients who are hypersensitive to

       salicylates

B    is indicated for diverticular disease

C    is available only as tablets

D    is not associated with side-effects related to blood disorders

E    is a prodrug of 5-aminosalicylic acid

9 COMMENTS

  1. Mesalazine (INN, BAN), also known as Mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an anti-inflammatory drug used to treat inflammation of the digestive tract (Crohn’s disease) and mild to moderate ulcerative colitis. Mesalazine is a bowel-specific aminosalicylate drug that is metabolized in the gut and has its predominant actions there, thereby having fewer systemic side effects. As a derivative of salicylic acid, 5-ASA is also an antioxidant that traps free radicals, which are potentially damaging by-products of metabolism.

  2. An anti-inflammatory agent, structurally related to the salicylates, which is active in inflammatory bowel disease. It is considered to be the active moiety of sulphasalazine. (From Martindale, The Extra Pharmacopoeia, 30th ed)

  3. is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn’s disease.

LEAVE A REPLY

Please enter your comment!
Please enter your name here