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Which drug can cause gray baby syndrome due to immature UDP-glucuronyl transferase activity in neonates?

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PANS QUIZ

Which drug can cause gray baby syndrome due to immature UDP-glucuronyl transferase activity in neonates?
A. Chloramphenicol
B. Sulfonamides
C. Gentamicin
D. Vancomycin

A patient receives a 400 mg IV bolus dose of a drug with a clearance of 4 L/hr and a volume of distribution of 40 L. Assuming first-order elimination, what is the drug’s elimination half-life?
A. 4.0 hr
B. 6.9 hr
C. 8.0 hr
D. 10.0 hr

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