Which of the following disadvantages does not limit using benzodiazepines as antianxiety agents?

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Which of the following disadvantages does not limit using benzodiazepines as antianxiety agents?

a) Tendency to develop psychologic dependence
b) A high risk of drug interactions based on liver enzyme induction

c) Synergic CNS depression with concomitant use of other drugs
d) The formation of active metabolites

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