1. Which of the following is the best example of a narrow therapeutic index medicine?
A. Paracetamol at therapeutic doses
B. Warfarin
C. Amoxicillin
D. Omeprazole
2. Which phase of a clinical trial primarily focuses on evaluating a medicine’s efficacy and common short-term adverse effects in a larger group of patients with the target disease?
A. Phase III
B. Phase II
C. Phase IV
D. Phase I
3. A patient takes a medicine that strongly inhibits CYP3A4. Which outcome is most likely if the patient’s other medicine is primarily metabolized by CYP3A4?
A. The second medicine may have increased plasma concentration
B. The second medicine must be absorbed more slowly
C. The second medicine becomes chemically identical to the inhibitor
D. The second medicine will always have zero plasma concentration
4. Which dosage form is specifically designed to release its drug gradually over an extended period rather than all at once?
A. Dispersible tablet
B. Immediate-release tablet
C. Effervescent tablet
D. Modified-release tablet
1. B
2. B
3. A
4. D
B
B
A
D
𝑩
𝑩
𝑨
𝑫
B
B
A
D
B
B
A
D
B
B
A
D
1.B
2.B
3.A
4.D
B
B
A
D