What do you know about Leflunomide


A its therapeutic effect starts after 4–6 weeks
B is given as an initial dose of 7.5 mg
C is administered once a week
D is available only for parenteral administration
E no washout procedures are required when changing to
another product


  1. The answer is A and all respondents got it, but the first to answer correctly is Hendrix.

    Leflunomide is a disease-modifying antirheumatic drug that exerts its
    therapeutic effect 4–6 weeks after initiation of treatment. It is started at 100 mg
    once daily for 3 days and then a maintenance dose of 10–20 mg once daily
    is recommended. It is available as tablets at 10 mg, 20 mg or 100 mg
    strengths. The active metabolite of leflunomide persists for a long period, so
    washout procedures are required in case of serious adverse effects or before
    changing to another disease-modifying antirheumatic drug.


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