Which of the following statements best describes a lead compound?

Which of the following statements best describes a lead compound?
a) A compound that contains the element lead
b) A compound from the research laboratory that is chosen to go forward for preclinical and
clinical trials.
c) A molecule that shows some activity or property of interest and serves as the starting point
for the development of a drug.
d) The first compound of a structural class of compounds to reach the market.

GCP are seen in all of the following except
a) Phase I trial
b)Phase II trial
c)Placebo effect
d)Preclinical trials